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Issue 31, 2008
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Synthesis and functionalization of magnetite nanoparticles with aminopropylsilane and carboxymethyldextran

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Abstract

Magnetite nanoparticles were functionalized with carboxymethyldextran (CMDx) covalently attached to the particles to prevent polymer desorption in biomedical applications. Carbodiimide chemistry was used to react carboxylic groups (–COOH) present in the CMDx molecule with amine end groups (NH2) previously grafted onto the nanoparticle surface by condensation of aminopropylsilane (APS) molecules. This method produces highly stable suspensions of magnetite nanoparticles with electrostatic and steric repulsion and no particle precipitation in the presence of electrolytes.

Graphical abstract: Synthesis and functionalization of magnetite nanoparticles with aminopropylsilane and carboxymethyldextran

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Publication details

The article was received on 28 Mar 2008, accepted on 27 May 2008 and first published on 03 Jul 2008


Article type: Paper
DOI: 10.1039/B805256E
Citation: J. Mater. Chem., 2008,18, 3650-3654

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    Synthesis and functionalization of magnetite nanoparticles with aminopropylsilane and carboxymethyldextran

    A. P. Herrera, C. Barrera and C. Rinaldi, J. Mater. Chem., 2008, 18, 3650
    DOI: 10.1039/B805256E

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