Issue 44, 2008

Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

Abstract

Hyperbranched polyglycerols (HPGs) are ideal scaffolds for the multivalent presentation of saccharides, due to their biocompatible, carbohydrate-like properties; here, we report the conjugation of galactose sugar moieties to HPG, and the multivalent effect of these constructs on selectin binding.

Graphical abstract: Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

Supplementary files

Article information

Article type
Communication
Submitted
01 Aug 2008
Accepted
11 Sep 2008
First published
03 Oct 2008

Chem. Commun., 2008, 5851-5853

Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

I. Papp, J. Dernedde, S. Enders and R. Haag, Chem. Commun., 2008, 5851 DOI: 10.1039/B813414F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements