Issue 42, 2008
From the journal:

Chemical Communications

A bromocoumarin-based linker for synthesis of photocleavable peptidoconjugates with high photosensitivity†

Kentaro Katayama,a   Shinya Tsukiji,a   Toshiaki Furutade  and  Teruyuki Nagamune*abc  

* Corresponding authors

a Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan

b Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
E-mail: nagamune@bioeng.t.u-tokyo.ac.jp
Fax: +81 (0)3 5841 8657
Tel: +81 (0)3 5841 7328

c Center for NanoBio Integration, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan

d Department of Biomolecular Science, Toho University, 2-2-1 Miyama, Funabashi, Japan

e Research Center for Materials with Integrated Properties, Toho University, 2-2-1 Miyama, Funabashi, Japan

Abstract

A new bromocoumarin-based bi-functional linker was developed for preparing photocleavable peptides and proteins with high photolytic efficiency, which have many potential applications in the study and engineering of biological systems.

Graphical abstract: A bromocoumarin-based linker for synthesis of photocleavable peptidoconjugates with high photosensitivity

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Article information

DOI
https://doi.org/10.1039/B812058G
Article type
Communication
Submitted
15 Jul 2008
Accepted
08 Aug 2008
First published
19 Sep 2008

Chem. Commun., 2008, 5399-5401

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A bromocoumarin-based linker for synthesis of photocleavable peptidoconjugates with high photosensitivity

K. Katayama, S. Tsukiji, T. Furuta and T. Nagamune, Chem. Commun., 2008, 5399 DOI: 10.1039/B812058G

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