Issue 42, 2008
From the journal:

Chemical Communications

Enantioselective synthesis of cyclopropylcarboxamides using s-BuLi–sparteine-mediated metallation†

Stephanie Lauru,a   Nigel S. Simpkins,‡*a   David Gethinb  and  Claire Wilsona  

* Corresponding authors

a School of Chemistry, The University of Nottingham, University Park, Nottingham, UK
E-mail: n.simpkins@bham.ac.uk
Fax: +44 121 4144403
Tel: +44 121 4148905

b Pfizer Central Research, Ramsgate Road, Sandwich, Kent, UK

Abstract

Enantioselective synthesis of cyclopropylcarboxamides is possible by asymmetric metallation of prochiral starting cyclopropanes using s-BuLi–sparteine.

Graphical abstract: Enantioselective synthesis of cyclopropylcarboxamides using s-BuLi–sparteine-mediated metallation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B810441G
Article type
Communication
Submitted
19 Jun 2008
Accepted
07 Aug 2008
First published
16 Sep 2008

Chem. Commun., 2008, 5390-5392

Permissions

Request permissions

Enantioselective synthesis of cyclopropylcarboxamides using s-BuLi–sparteine-mediated metallation

S. Lauru, N. S. Simpkins, D. Gethin and C. Wilson, Chem. Commun., 2008, 5390 DOI: 10.1039/B810441G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements