Issue 39, 2008
From the journal:

Chemical Communications

trans-2-Aminocyclohexanol as a pH-sensitive conformational switch in lipid amphiphiles†‡

Barbora Brazdova,a   Ningrong Zhang,b   Vyacheslav V. Samoshin*a  and  Xin Guo*b  

* Corresponding authors

a Department of Chemistry, University of the Pacific, Stockton, USA
E-mail: vsamoshin@pacific.edu
Fax: +1 209-946-2607
Tel: +1 209-946-2921

b Department of Pharmaceutics and Medicinal Chemistry, TLJ School of Pharmacy and Health Sciences, University of the Pacific, Stockton, USA
E-mail: xguo@pacific.edu
Fax: +1 209-946-2410
Tel: +1 209-946-2321

Abstract

Protonation-induced conformational change of lipid tails is reported as a novel strategy to render pH-sensitive lipid amphiphiles and lipidcolloids.

Graphical abstract: trans-2-Aminocyclohexanol as a pH-sensitive conformational switch in lipid amphiphiles

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Article information

DOI
https://doi.org/10.1039/B807704E
Article type
Communication
Submitted
07 May 2008
Accepted
18 Jun 2008
First published
05 Aug 2008

Chem. Commun., 2008, 4774-4776

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trans-2-Aminocyclohexanol as a pH-sensitive conformational switch in lipid amphiphiles

B. Brazdova, N. Zhang, V. V. Samoshin and X. Guo, Chem. Commun., 2008, 4774 DOI: 10.1039/B807704E

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