Issue 16, 2008
From the journal:

Chemical Communications

Ni–nitrilotriacetic acid-modified quantum dots as a site-specific labeling agent of histidine-tagged proteins in live cells†

Junwon Kim,‡a   Hye-Young Park,a   Jaeseung Kim,‡a   Jiyoung Ryu,a   Do Yoon Kwon,b   Regis Grailheb  and  Rita Song*a  

* Corresponding authors

a Nano/Bio Chemistry Laboratory, Institut Pasteur Korea (IP-K), 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, Korea
E-mail: rsong@ip-korea.org
Fax: +82-31-546-6710
Tel: +82-31-546-6701

b Dynamic Imaging Platform Group, Institut Pasteur Korea (IP-K), 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, Korea

Abstract

Ni–nitrilotriacetic acid (NTA) functionalized CdSe/ZnS quantum dots (QDs) were exploited as a site-specific labeling agent of histidine-tagged biomolecules in live cells; the QDs were found to be water-soluble, aggregation free and stable for several months.

Graphical abstract: Ni–nitrilotriacetic acid-modified quantum dots as a site-specific labeling agent of histidine-tagged proteins in live cells

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Article information

DOI
https://doi.org/10.1039/B719434J
Article type
Communication
Submitted
17 Dec 2007
Accepted
24 Jan 2008
First published
19 Feb 2008

Chem. Commun., 2008, 1910-1912

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Ni–nitrilotriacetic acid-modified quantum dots as a site-specific labeling agent of histidine-tagged proteins in live cells

J. Kim, H. Park, J. Kim, J. Ryu, D. Y. Kwon, R. Grailhe and R. Song, Chem. Commun., 2008, 1910 DOI: 10.1039/B719434J

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