Issue 23, 2008
From the journal:

Organic & Biomolecular Chemistry

Directed epoxidation of cyclohexa-1,4-dienes–stereoselective formation of up to six contiguous stereogenic centres†

Michael Butters,b   Dirk J. Beetstra,a   Mark C. Elliott,*a   Joseph Hill-Cousinsa  and  Benson M. Kariukia  

* Corresponding authors

a School of Chemistry, Cardiff University, Park Place, Cardiff, UK,
E-mail: elliottmc@cardiff.ac.uk
Fax: +44 (0)29 20874030
Tel: +44 (0)29 20874686

b AstraZeneca Process R & D Avlon/Charnwood, Avlon Works, Severn Road, Hallen, Bristol, UK,

Abstract

Epoxidation/cyclisation of cyclohexa-1,4-dienes containing pendant hydroxyl groups provides stereocontrolled access to highly-functionalised reduced benzol[b]furan derivatives.

Graphical abstract: Directed epoxidation of cyclohexa-1,4-dienes–stereoselective formation of up to six contiguous stereogenic centres

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Article information

DOI
https://doi.org/10.1039/B814131M
Article type
Paper
Submitted
13 Aug 2008
Accepted
29 Aug 2008
First published
20 Oct 2008

Org. Biomol. Chem., 2008,6, 4426-4434

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Directed epoxidation of cyclohexa-1,4-dienes–stereoselective formation of up to six contiguous stereogenic centres

M. Butters, D. J. Beetstra, M. C. Elliott, J. Hill-Cousins and B. M. Kariuki, Org. Biomol. Chem., 2008, 6, 4426 DOI: 10.1039/B814131M

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