Issue 13, 2008

Solid-phase synthesis of a lysine-capped bis-dendron with remarkable DNA delivery abilities

Abstract

Solid-phase synthesis of a generation 3.0 polyamidourea 1→3 C-branched bis-dendron followed by capping of the peripheral amino groups with L-lysine gave an efficient transfection reagent.

Graphical abstract: Solid-phase synthesis of a lysine-capped bis-dendron with remarkable DNA delivery abilities

Supplementary files

Article information

Article type
Communication
Submitted
20 Mar 2008
Accepted
30 Apr 2008
First published
12 May 2008

Org. Biomol. Chem., 2008,6, 2266-2269

Solid-phase synthesis of a lysine-capped bis-dendron with remarkable DNA delivery abilities

S. How, A. Unciti-Broceta, R. M. Sánchez-Martín and M. Bradley, Org. Biomol. Chem., 2008, 6, 2266 DOI: 10.1039/B804771E

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