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Issue 4, 2008
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Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

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Abstract

Covering: 1990 to February 2008

This review surveys efforts to reconstitute key steps in polyketide and nonribosomal peptide biosynthetic pathways with purified enzymes and substrates; 344 references are cited.

Graphical abstract: Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

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Article information


Submitted
28 Feb 2008
First published
23 May 2008

Nat. Prod. Rep., 2008,25, 757-793
Article type
Review Article

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

E. S. Sattely, M. A. Fischbach and C. T. Walsh, Nat. Prod. Rep., 2008, 25, 757
DOI: 10.1039/B801747F

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