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Issue 10, 2008
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Formation of artificial lipid bilayers using droplet dielectrophoresis

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Abstract

We describe the formation of artificial bilayer lipid membranes (BLMs) by the controlled, electrical manipulation of aqueous droplets immersed in a lipidalkane solution. Droplet movement was generated using dielectrophoresis on planar microelectrodes covered in a thin insulator. Droplets, surrounded by lipid monolayers, were brought into contact and spontaneously formed a BLM. The method produced BLMs suitable for single-channel recording of membrane protein activity and the technique can be extended to create programmable BLM arrays and networks.

Graphical abstract: Formation of artificial lipid bilayers using droplet dielectrophoresis

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Publication details

The article was received on 30 Apr 2008, accepted on 05 Aug 2008 and first published on 13 Aug 2008


Article type: Communication
DOI: 10.1039/B807374K
Lab Chip, 2008,8, 1617-1620

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    Formation of artificial lipid bilayers using droplet dielectrophoresis

    S. Aghdaei, M. E. Sandison, M. Zagnoni, N. G. Green and H. Morgan, Lab Chip, 2008, 8, 1617
    DOI: 10.1039/B807374K

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