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Issue 11, 2008
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Pillar-induced droplet merging in microfluidic circuits

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Abstract

A novel method is presented for controllably merging aqueous microdroplets within segmented flow microfluidic devices. Our approach involves exploiting the difference in hydrodynamic resistance of the continuous phase and the surface tension of the discrete phase through the use of passive structures contained within a microfluidic channel. Rows of pillars separated by distances smaller than the representative droplet dimension are installed within the fluidic network and define passive merging elements or chambers. Initial experiments demonstrate that such a merging element can controllably adjust the distance between adjacent droplets. In a typical scenario, a droplet will enter the chamber, slow down and stop. It will wait and then merge with the succeeding droplets until the surface tension is overwhelmed by the hydraulic pressure. We show that such a merging process is independent of the inter-droplet separation but rather dependent on the droplet size. Moreover, the number of droplets that can be merged at any time is also dependent on the mass flow rate and volume ratio between the droplets and the merging chamber. Finally, we note that the merging of droplet interfaces occurs within both compressing and the decompressing regimes.

Graphical abstract: Pillar-induced droplet merging in microfluidic circuits

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Publication details

The article was received on 01 Aug 2008, accepted on 08 Sep 2008 and first published on 08 Oct 2008


Article type: Paper
DOI: 10.1039/B813325E
Lab Chip, 2008,8, 1837-1841

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    Pillar-induced droplet merging in microfluidic circuits

    X. Niu, S. Gulati, J. B. Edel and A. J. deMello, Lab Chip, 2008, 8, 1837
    DOI: 10.1039/B813325E

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