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Issue 5, 2008
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Tip-enhanced Raman scattering

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Tip-enhanced Raman scattering (TERS) is a technique that provides molecular information on the nanometre scale. Using a nanometre-sized metal particle results in a strong signal enhancement and a lateral resolution similar to the dimensions of the particle. As TERS is in a way the ultimate SERS experiment, the theoretical background will be briefly discussed with respect to the unique features and the specific effects that occur when only a single nanoparticle is used as a probe. All the major parts of the instrument will be revealed and the specific advantages of the different instrumental set ups will be investigated with respect to the particular requirements of the sample. Selected examples ranging from material science to cell biological applications demonstrate the capabilities and the potential of TERS in this tutorial review.

Graphical abstract: Tip-enhanced Raman scattering

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Article information

17 Mar 2008
First published
31 Mar 2008

Chem. Soc. Rev., 2008,37, 921-930
Article type
Tutorial Review

Tip-enhanced Raman scattering

E. Bailo and V. Deckert, Chem. Soc. Rev., 2008, 37, 921
DOI: 10.1039/B705967C

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