Jump to main content
Jump to site search

Issue 2, 2008
Previous Article Next Article

Fluorine in medicinal chemistry

Author affiliations


It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.

Graphical abstract: Fluorine in medicinal chemistry

Back to tab navigation

Publication details

The article was received on 26 Nov 2007 and first published on 13 Dec 2007

Article type: Tutorial Review
DOI: 10.1039/B610213C
Chem. Soc. Rev., 2008,37, 320-330

  •   Request permissions

    Fluorine in medicinal chemistry

    S. Purser, P. R. Moore, S. Swallow and V. Gouverneur, Chem. Soc. Rev., 2008, 37, 320
    DOI: 10.1039/B610213C

Search articles by author