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Issue 37, 2008
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Selective synthesis of double temperature-sensitive polymer–peptide conjugates

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Abstract

A novel synthetic route has been developed to couple selectively a modified octa-peptide, that is able to gel at low temperature, to the prototypical thermoresponsive polymer poly(N-isopropylacrylamide) to give a bioconjugate that exhibits double thermoresponsiveness.

Graphical abstract: Selective synthesis of double temperature-sensitive polymer–peptide conjugates

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Article information


Submitted
22 Apr 2008
Accepted
16 May 2008
First published
16 Jul 2008

Chem. Commun., 2008, 4433-4435
Article type
Communication

Selective synthesis of double temperature-sensitive polymerpeptide conjugates

F. Stoica, C. Alexander, N. Tirelli, A. F. Miller and A. Saiani, Chem. Commun., 2008, 4433
DOI: 10.1039/B806782A

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