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Issue 17, 2008
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Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC

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Abstract

Single molecule fluorescence spectroscopy has been employed to resolve the conformational heterogeneity, hybridization kinetics and study mutational effects on the c-MYC promoter G-quadruplex.

Graphical abstract: Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC

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Supplementary files

Article information


Submitted
25 Jan 2008
Accepted
26 Feb 2008
First published
20 Mar 2008

Chem. Commun., 2008, 2007-2009
Article type
Communication

Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC

P. S. Shirude, L. Ying and S. Balasubramanian, Chem. Commun., 2008, 2007
DOI: 10.1039/B801465E

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