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Issue 25, 2008
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8-Amino guanine accelerates tetramolecular G-quadruplex formation

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Abstract

We demonstrate here that 8-amino guanine (R) strongly accelerates quadruplex formation, which makes this nucleobase the most attractive replacement for guanine in the context of tetramolecular parallel quadruplexes.

Graphical abstract: 8-Amino guanine accelerates tetramolecular G-quadruplex formation

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Publication details

The article was received on 22 Jan 2008, accepted on 11 Mar 2008 and first published on 15 Apr 2008


Article type: Communication
DOI: 10.1039/B801221K
Chem. Commun., 2008, 2926-2928

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    8-Amino guanine accelerates tetramolecular G-quadruplex formation

    J. Gros, A. Aviñó, J. Lopez de la Osa, C. González, L. Lacroix, A. Pérez, M. Orozco, R. Eritja and J. Mergny, Chem. Commun., 2008, 2926
    DOI: 10.1039/B801221K

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