Jump to main content
Jump to site search

Issue 9, 2008
Previous Article Next Article

Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

Author affiliations

Abstract

A safe, functional-group-tolerant and high-throughput version of the trimethylaluminium mediated amide bond formation reaction has been developed in a microreactor system; rimonabant and efaproxiral were prepared to illustrate the utility of the method.

Graphical abstract: Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Dec 2007, accepted on 16 Jan 2008 and first published on 01 Feb 2008


Article type: Communication
DOI: 10.1039/B719603B
Chem. Commun., 2008, 1100-1102

  •   Request permissions

    Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

    T. Gustafsson, F. Pontén and P. H. Seeberger, Chem. Commun., 2008, 1100
    DOI: 10.1039/B719603B

Search articles by author

Spotlight

Advertisements