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Issue 44, 2008
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How to very efficiently functionalize gold nanoparticles by “click” chemistry

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Abstract

Difficulties previously encountered in the very useful “click” functionalization of gold nanoparticles (AuNPs) resulting in low yields are now overcome by using specific conditions: 1 : 1 waterTHF medium, stoichiometric CuSO4 and sodium ascorbate, inert atmosphere at 20 °C that provide quantitative “click” reactions between azidoalkylthiolate-AuNPs with various hydrophilic (PEG-containing) and hydrophobic (organic and organometallic) alkynes.

Graphical abstract: How to very efficiently functionalize gold nanoparticles by “click” chemistry

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Article information


Submitted
17 Jul 2008
Accepted
09 Sep 2008
First published
01 Oct 2008

Chem. Commun., 2008, 5788-5790
Article type
Communication

How to very efficiently functionalize gold nanoparticles by “click” chemistry

E. Boisselier, L. Salmon, J. Ruiz and D. Astruc, Chem. Commun., 2008, 5788
DOI: 10.1039/B812249K

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