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Issue 41, 2008
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Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

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Abstract

A molecular beacon that incorporates components of an artificially expanded genetic information system (AEGIS) in its stem is shown not to be opened by unwanted stem invasion by adventitious standard DNA; this should improve the “darkness” of the beacon in real-world applications.

Graphical abstract: Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

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Article information


Submitted
07 Jul 2008
Accepted
11 Aug 2008
First published
26 Sep 2008

Chem. Commun., 2008, 5128-5130
Article type
Communication

Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

P. Sheng, Z. Yang, Y. Kim, Y. Wu, W. Tan and S. A. Benner, Chem. Commun., 2008, 5128 DOI: 10.1039/B811159F

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