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Issue 25, 2008
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2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines

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Abstract

Microwave irradiations of 2-(aminoaryl)alkanone O-phenyl oximes and carbonyl compounds generate iminyl radicals in company with imines; iminyl on imine ring closure yields dihydroquinazolines or quinazolines when ZnCl2 is included in the mixture.

Graphical abstract: 2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines

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Article information


Submitted
03 Mar 2008
Accepted
12 Mar 2008
First published
17 Apr 2008

Chem. Commun., 2008, 2935-2937
Article type
Communication

2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines

F. Portela-Cubillo, J. S. Scott and J. C. Walton, Chem. Commun., 2008, 2935
DOI: 10.1039/B803630F

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