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Diastereomeric doubly bridged biphenyl azepines, atropos at 20 °C and tropos at 80 °C, are precursors to effective iminium organocatalysts that are employed in the enantioselective epoxidation of prochiral olefins (up to 85% ee).

Graphical abstract: On the enantioselective olefin epoxidation by doubly bridged biphenyl azepine derivatives – mixed tropos/atropos chiral biaryls

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