1,3,4-Thiadiazole-2-carboxylate esters: new synthetic methodology for the preparation of an elusive family of self-organizing materials
Abstract
A series of alkyl 5-(4-octyloxyphenyl)-1,3,4-thiadiazole-2-carboxylates has been prepared via a novel chemoselective ring-closure of appropriate tricarbonyl precursors. This paper represents the first report of a general and reproducible synthetic methodology for the preparation of 1,3,4-thiadiazole-2-carboxylate