Issue 38, 2007
From the journal:

Chemical Communications

Fluorous tagged small molecule microarrays†

Rebecca L. Nicholson,a   Mark L. Ladlowb  and  David R. Springa  

a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: drspring@ch.cam.ac.uk
Tel: +44 (0)1223 336498

b GSK Cambridge Technology Centre, Lensfield Road, Cambridge, UK

Abstract

The affinity fluorous interaction between fluorous tagged small molecules and a fluoroalkyl modified glass surface was shown to facilitate the detection of protein–ligand binding interactions in the fabrication and screening of small molecule microarrays.

Graphical abstract: Fluorous tagged small molecule microarrays

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Article information

DOI
https://doi.org/10.1039/B712906H
Article type
Communication
Submitted
21 Aug 2007
Accepted
03 Sep 2007
First published
04 Sep 2007

Chem. Commun., 2007, 3906-3908

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Fluorous tagged small molecule microarrays

R. L. Nicholson, M. L. Ladlow and D. R. Spring, Chem. Commun., 2007, 3906 DOI: 10.1039/B712906H

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