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Issue 40, 2007
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A highly stereocontrolled total synthesis of dysiherbaine

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Abstract

A total synthesis of dysiherbaine, a potent agonist of AMPA-KA type glutamate receptors, has been accomplished in completely stereocontrolled manner starting from tri-O-acetyl-D-galactal in 25 steps and in 3% overall yield.

Graphical abstract: A highly stereocontrolled total synthesis of dysiherbaine

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Article information


Submitted
27 Jun 2007
Accepted
13 Jul 2007
First published
06 Aug 2007

Chem. Commun., 2007, 4158-4160
Article type
Communication

A highly stereocontrolled total synthesis of dysiherbaine

K. Takahashi, T. Matsumura, J. Ishihara and S. Hatakeyama, Chem. Commun., 2007, 4158
DOI: 10.1039/B709627E

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