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Issue 40, 2007
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Iterative approach to polyketide-type structures: stereoselective synthesis of 1,3-polyols utilizing the catalytic asymmetric Overman esterification

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Abstract

An iterative systematic approach to the 1,3-polyol motif has been developed to provide access to all possible stereoisomers by utilizing the catalytic asymmetric Overman esterification for the construction of all stereogenic centres.

Graphical abstract: Iterative approach to polyketide-type structures: stereoselective synthesis of 1,3-polyols utilizing the catalytic asymmetric Overman esterification

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Article information


Submitted
31 May 2007
Accepted
19 Jul 2007
First published
06 Aug 2007

Chem. Commun., 2007, 4164-4166
Article type
Communication

Iterative approach to polyketide-type structures: stereoselective synthesis of 1,3-polyols utilizing the catalytic asymmetric Overman esterification

J. T. Binder and S. F. Kirsch, Chem. Commun., 2007, 4164
DOI: 10.1039/B708248G

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