Cavity effect amplification in the recognition of dicarboxylic acids by initial ditopic H-bond formation followed by kinetic trapping†
Abstract
Di[dihydroxotin(IV)] Tröger's base bis-porphyrin 1, a host molecule with two internal and two external guest interaction sites, binds ≤ 1 equivalent of dicarboxylic acid quantitatively within the chiral cavity, a regioselectivity amplified by initial ditopic H-bond formation, followed by kinetic trapping.