Double strand DNA cleavage with a binuclear iron complex†
Abstract
Covalently linking two single strand DNA cleaving agents resulted in a new biomimetic binuclear iron complex capable of effecting oxidative double strand DNA cleavage.
* Corresponding authors
a
Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, Groningen, The Netherlands
E-mail:
B.L.Feringa@rug.nl, J.G.Roelfes@rug.nl
Fax: +31 50 3634296
Tel: +31 50 3637745
Covalently linking two single strand DNA cleaving agents resulted in a new biomimetic binuclear iron complex capable of effecting oxidative double strand DNA cleavage.
T. A. van den Berg, B. L. Feringa and G. Roelfes, Chem. Commun., 2007, 180 DOI: 10.1039/B613469F
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