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Issue 10, 2007
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[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

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Abstract

The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.

Graphical abstract: [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

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Publication details

The article was received on 27 Feb 2007, accepted on 19 Mar 2007 and first published on 16 Apr 2007


Article type: Paper
DOI: 10.1039/B702995K
Org. Biomol. Chem., 2007,5, 1559-1561

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    [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

    C. D. Smith, I. R. Baxendale, S. Lanners, J. J. Hayward, S. C. Smith and S. V. Ley, Org. Biomol. Chem., 2007, 5, 1559
    DOI: 10.1039/B702995K

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