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Issue 7, 2007
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Photochemical control of biological processes

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Photochemical regulation of biological processes offers a high level of control to study intracellular mechanisms with unprecedented spatial and temporal resolution. This report summarizes the advances made in recent years, focusing predominantly on the in vivo regulation of gene function using irradiation with UV light. The majority of the described applications entail the utilization of photocaging groups installed either on a small molecule modulator of biomolecular function or directly on a biological macromolecule itself.

Graphical abstract: Photochemical control of biological processes

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The article was received on 09 Nov 2006, accepted on 07 Dec 2006 and first published on 20 Dec 2006

Article type: Emerging Area
DOI: 10.1039/B616410M
Org. Biomol. Chem., 2007,5, 999-1005

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    Photochemical control of biological processes

    D. D. Young and A. Deiters, Org. Biomol. Chem., 2007, 5, 999
    DOI: 10.1039/B616410M

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