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Issue 1, 2007
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Synthesis of protein–polymer conjugates

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Abstract

Protein–polymer conjugates are widely employed for applications in medicine, biotechnology and nanotechnology. Covalent attachment of synthetic polymers to proteins improves protein stability, solubility, and biocompatibility. Furthermore, synthetic polymers impart new properties such as self assembly and phase behavior. Polymer attachment at amino acid side-chains and at ligand binding sites is typically exploited. This Emerging Area focuses on synthetic methods to prepare protein-reactive polymers and also employing the protein itself as an initiator for polymerization.

Graphical abstract: Synthesis of protein–polymer conjugates

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Publication details

The article was received on 29 Aug 2006, accepted on 12 Oct 2006 and first published on 08 Nov 2006


Article type: Emerging Area
DOI: 10.1039/B612355D
Org. Biomol. Chem., 2007,5, 45-53

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    Synthesis of protein–polymer conjugates

    K. L. Heredia and H. D. Maynard, Org. Biomol. Chem., 2007, 5, 45
    DOI: 10.1039/B612355D

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