Jump to main content
Jump to site search

Issue 3, 2007
Previous Article Next Article

Heme and virulence: how bacterial pathogens regulate, transport and utilize heme

Author affiliations

Abstract

Covering: 2000–2006

The ability of bacterial pathogens to obtain iron is essential for their survival, and the expression of such virulence factors is (in part) essential for establishing and maintaining infection. As such, pathogenic bacteria have evolved numerous sophisticated mechanisms whereby they utilize the host's heme containing proteins as a source of iron. In the following review we will summarize the current knowledge on the mechanisms by which heme is transported and utilized by bacterial pathogens.

Graphical abstract: Heme and virulence: how bacterial pathogens regulate, transport and utilize heme

  • This article is part of the themed collection: Heme
Back to tab navigation

Publication details

The article was received on 21 Dec 2006 and first published on 11 Apr 2007


Article type: Review Article
DOI: 10.1039/B604193K
Nat. Prod. Rep., 2007,24, 511-522

  •   Request permissions

    Heme and virulence: how bacterial pathogens regulate, transport and utilize heme

    A. Wilks and K. A. Burkhard, Nat. Prod. Rep., 2007, 24, 511
    DOI: 10.1039/B604193K

Search articles by author

Spotlight

Advertisements