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Issue 10, 2007
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Addressing a vascular endothelium array with blood components using underlying microfluidic channels

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Abstract

Here, we show that an array of endothelial cells, addressable by an underlying microfluidic network of channels containing red blood cells, can be employed as an in vitro model of in vivo circulation to monitor cellular communication between different cell types in the drug discovery process.

Graphical abstract: Addressing a vascular endothelium array with blood components using underlying microfluidic channels

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Publication details

The article was received on 16 Aug 2007, accepted on 31 Aug 2007 and first published on 05 Sep 2007


Article type: Communication
DOI: 10.1039/B712619K
Lab Chip, 2007,7, 1256-1259

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    Addressing a vascular endothelium array with blood components using underlying microfluidic channels

    L. I. Genes, N. V. Tolan, M. K. Hulvey, R. S. Martin and D. M. Spence, Lab Chip, 2007, 7, 1256
    DOI: 10.1039/B712619K

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