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Issue 38, 2007
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The bioinorganic and medicinal chemistry of carboranes: from new drug discovery to molecular imaging and therapy

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Abstract

The role of carboranes in medicinal chemistry has diversified in recent years and now extends into areas of drug discovery, molecular imaging, and targeted radionuclide therapy. An introduction to carborane chemistry is provided to familiarize the non-expert with some key properties of these molecules, followed by an overview of current medicinally-orientated research involving carboranes. The broad-ranging nature of this research is illustrated, with emphasis placed on recent highlights and advances in this field.

Graphical abstract: The bioinorganic and medicinal chemistry of carboranes: from new drug discovery to molecular imaging and therapy

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Article information


Submitted
28 Jun 2007
Accepted
14 Aug 2007
First published
11 Sep 2007

Dalton Trans., 2007, 4240-4251
Article type
Perspective

The bioinorganic and medicinal chemistry of carboranes: from new drug discovery to molecular imaging and therapy

A. F. Armstrong and J. F. Valliant, Dalton Trans., 2007, 4240
DOI: 10.1039/B709843J

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