Issue 6, 2007

Application of electronic circular dichroism in configurational and conformational analysis of organic compounds

Abstract

This tutorial review is addressed to readers with a background in basic organic chemistry and spectroscopy, but without a specific knowledge of electronic circular dichroism. It describes the fundamental principles, instrumentation, data analysis, and different approaches for interpretation of ECD. The discussion focuses on the application of ECD, also in combination with other methods, in structural analysis of organic compounds, including host–guest complexes, and will emphasize the importance of the interplay between configurational and conformational factors. The tutorial also covers modern supramolecular aspects of ECD and recent developments in computational methods.

Graphical abstract: Application of electronic circular dichroism in configurational and conformational analysis of organic compounds

Article information

Article type
Tutorial Review
Submitted
16 Nov 2006
First published
05 Feb 2007

Chem. Soc. Rev., 2007,36, 914-931

Application of electronic circular dichroism in configurational and conformational analysis of organic compounds

N. Berova, L. D. Bari and G. Pescitelli, Chem. Soc. Rev., 2007, 36, 914 DOI: 10.1039/B515476F

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