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Issue 7, 2007
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Direct transition metal-catalyzed functionalization of heteroaromatic compounds

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Abstract

During the last two decades there has been considerable growth in the development of catalytic reactions capable of activating unreactive C–H bonds. These methods allow for the synthesis of complex molecules from easily available and cheaper precursors in a fewer number of steps. Naturally, the development of C–H activation methods for direct functionalization of heterocyclic molecules, invaluable building blocks for pharmaceutical and synthetic chemistry and material science, has received substantial attention as well. This critical review summarizes the progress made in this field until November 2006 (117 references).

Graphical abstract: Direct transition metal-catalyzed functionalization of heteroaromatic compounds

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Article information


Submitted
06 Dec 2006
First published
05 Mar 2007

Chem. Soc. Rev., 2007,36, 1173-1193
Article type
Critical Review

Direct transition metal-catalyzed functionalization of heteroaromatic compounds

I. V. Seregin and V. Gevorgyan, Chem. Soc. Rev., 2007, 36, 1173 DOI: 10.1039/B606984N

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