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Issue 6, 2007
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Solvent-free synthesis of metal complexes

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Avoiding the use of solvents in synthesis can reduce environmental contamination and even be more convenient than using solvent-based synthesis. In this tutorial review we focus on recent research into the use of mechanochemistry (grinding) to synthesise metal complexes in the absence of solvent. We include synthesis of mononuclear complexes, coordination clusters, spacious coordination cages, and 1-, 2- and 3-dimensional coordination polymers (metal organic frameworks) which can even exhibit microporosity. Remarkably, in many cases, mechanochemical synthesis is actually faster and more convenient than the original solvent-based methods. Examples of solvent-free methods other than grinding are also briefly discussed, and the positive outlook for this growing topic is emphasised.

Graphical abstract: Solvent-free synthesis of metal complexes

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Article information

31 Oct 2006
First published
19 Feb 2007

Chem. Soc. Rev., 2007,36, 846-855
Article type
Tutorial Review

Solvent-free synthesis of metal complexes

A. L. Garay, A. Pichon and S. L. James, Chem. Soc. Rev., 2007, 36, 846
DOI: 10.1039/B600363J

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