Issue 48, 2007
From the journal:

Chemical Communications

Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel†

Geo Paul,a   Stefan Steuernagelb  and  Hubert Koller*a  

* Corresponding authors

a Institut für Physikalische Chemie and Graduate School of Chemistry, Westfälische Wilhelms-Universität, Corrensstrasse 36, 48149 Münster, Germany
E-mail: hubert.koller@uni-muenster.de
Fax: +49 251 8323409
Tel: +49 251 8323448

b Bruker BioSpin GmbH, Silberstreifen 4, 76287 Rheinstetten, Germany

Abstract

The drug molecule Propranolol has been encapsulated by a sol–gel process in an organic–inorganic hybrid matrix by in-situ self-assembly; the 2D HETCOR solid state NMR spectroscopy provides direct proof of the intimate spatial relationship between the host matrix and guest drug molecules.

Graphical abstract: Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel

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Article information

DOI
https://doi.org/10.1039/B711105C
Article type
Communication
Submitted
19 Jul 2007
Accepted
11 Oct 2007
First published
17 Oct 2007

Chem. Commun., 2007, 5194-5196

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Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel

G. Paul, S. Steuernagel and H. Koller, Chem. Commun., 2007, 5194 DOI: 10.1039/B711105C

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