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Issue 46, 2007
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Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

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Abstract

We have developed a new biosensor architecture, which is comprised of a polypeptide–peptide nucleic acid tri-block co-polymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

Graphical abstract: Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

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Supplementary files

Article information


Submitted
30 Jun 2007
Accepted
20 Sep 2007
First published
26 Oct 2007

Chem. Commun., 2007, 4869-4871
Article type
Communication

Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

K. J. Oh, K. J. Cash, A. A. Lubin and K. W. Plaxco, Chem. Commun., 2007, 4869
DOI: 10.1039/B709776J

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