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Issue 46, 2007
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Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

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Abstract

We have developed a new biosensor architecture, which is comprised of a polypeptide–peptide nucleic acid tri-block co-polymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

Graphical abstract: Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

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Publication details

The article was received on 30 Jun 2007, accepted on 20 Sep 2007 and first published on 26 Oct 2007


Article type: Communication
DOI: 10.1039/B709776J
Chem. Commun., 2007, 4869-4871

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    Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

    K. J. Oh, K. J. Cash, A. A. Lubin and K. W. Plaxco, Chem. Commun., 2007, 4869
    DOI: 10.1039/B709776J

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