Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 47, 2007
Previous Article Next Article

Carboranyl thymidine analogues for neutron capture therapy

Author affiliations

Abstract

Neutron capture therapy (NCT) is a binary radio-chemotherapeutic modality for the treatment of cancer. A major focus of NCT-related research is the development of novel tumor-selective agents that serve as the chemical component in NCT. Thymidine analogues substituted with a boron-containing carborane cluster at the N3 position, designated 3CTAs (3-carboranyl thymidine analogues), constitute one class of these new improved NCT agents. Their chemical, structural and biological properties are discussed in this Feature Article.

Graphical abstract: Carboranyl thymidine analogues for neutron capture therapy

Back to tab navigation

Article information


Submitted
14 May 2007
Accepted
17 Jul 2007
First published
15 Aug 2007

Chem. Commun., 2007, 4978-4991
Article type
Feature Article

Carboranyl thymidine analogues for neutron capture therapy

W. Tjarks, R. Tiwari, Y. Byun, S. Narayanasamy and Rolf. F. Barth, Chem. Commun., 2007, 4978
DOI: 10.1039/B707257K

Social activity

Search articles by author

Spotlight

Advertisements