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Issue 28, 2007
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A novel class of metal-directed supramolecular DNA-delivery systems

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Abstract

The bis-complexes [Cu(Ldt)2](OTf)2 (1) and [Cu(Lot)2](OTf)2 (2), where Ldt = 1-dodecyl-1,4,7-triazacyclononane, Lot = 1-octadecyl-1,4,7-triazacyclononane and OTf = trifluoromethanesulfonate, formed a novel class of metallo-liposomes in water that transfect pEGFP-N1 plasmids into HEK 293-T cells at 38% and 4% efficiency, respectively.

Graphical abstract: A novel class of metal-directed supramolecular DNA-delivery systems

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Article information


Submitted
02 Mar 2007
Accepted
19 Apr 2007
First published
09 May 2007

Chem. Commun., 2007, 2944-2946
Article type
Communication

A novel class of metal-directed supramolecular DNA-delivery systems

I. Cruz-Campa, A. Arzola, L. Santiago, J. G. Parsons, A. Varela-Ramirez, R. J. Aguilera and J. C. Noveron, Chem. Commun., 2007, 2944
DOI: 10.1039/B703201C

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