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7-Methyl-8-oxo-2′-deoxyguanosine, an analogue of the abundant promutagen 8-oxo-2′-deoxyguanosine, was incorporated into oligonucleotides and tested for its stability in various base pairs.

Graphical abstract: Synthesis, oligonucleotide incorporation and base pair stability of 7-methyl-8-oxo-2′-deoxyguanosine

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