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Issue 16, 2006
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Variations of the P2 group in HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold

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Abstract

A short synthetic protocol leading to HIV-1 protease inhibitors with a tertiary alcohol based transition-state mimicking unit and different P2 side chains has been developed.

Graphical abstract: Variations of the P2 group in HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold

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Publication details

The article was received on 15 May 2006, accepted on 23 Jun 2006 and first published on 06 Jul 2006


Article type: Communication
DOI: 10.1039/B606859F
Citation: Org. Biomol. Chem., 2006,4, 3040-3043

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    Variations of the P2 group in HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold

    J. K. Ekegren, J. Gising, H. Wallberg, M. Larhed, B. Samuelsson and A. Hallberg, Org. Biomol. Chem., 2006, 4, 3040
    DOI: 10.1039/B606859F

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