Issue 6, 2006
From the journal:

CrystEngComm

Solvent mediated centric/non-centric polymorph pairs of an indole derivative: Subtle variation of C–H⋯O hydrogen bonds and C–H⋯π interactions†

Angshuman R. Choudhury,*a   Kuppuswamy Nagarajanb  and  Tayur N. Guru Row*c  

* Corresponding authors

a Department of Chemistry, University of Liverpool, Liverpool, UK
E-mail: angshu@liv.ac.uk

b HIKAL India Limited, Bannerghatta Road, Bangalore, Karnataka, India

c Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore, Karnataka, India
E-mail: ssctng@sscu.iisc.ernet.in
Fax: +91-80-23601310
Tel: +91-80-22932796

Abstract

Centric (P21/n) and non-centric (P21) polymorphic pairs of biologically active 1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one crystallized from different solvents have been elucidated via single crystal and powder X-ray diffraction studies, morphological observations and calorimetric measurements. C–H⋯O hydrogen bonding and weak intermolecular C–H⋯π interactions generate distinct packing features in the two forms.

Graphical abstract: Solvent mediated centric/non-centric polymorph pairs of an indole derivative: Subtle variation of C–H⋯O hydrogen bonds and C–H⋯π interactions

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B604118C
Article type
Paper
Submitted
20 Mar 2006
Accepted
25 May 2006
First published
08 Jun 2006

CrystEngComm, 2006,8, 482-488

Permissions

Request permissions

Solvent mediated centric/non-centric polymorph pairs of an indole derivative: Subtle variation of C–H⋯O hydrogen bonds and C–H⋯π interactions

A. R. Choudhury, K. Nagarajan and T. N. Guru Row, CrystEngComm, 2006, 8, 482 DOI: 10.1039/B604118C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements