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Issue 45, 2006
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Tetramethylpyridiniumporphyrazines—a new class of G-quadruplex inducing and stabilising ligands

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Abstract

3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.

Graphical abstract: Tetramethylpyridiniumporphyrazines—a new class of G-quadruplex inducing and stabilising ligands

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Article information


Submitted
15 Aug 2006
Accepted
12 Sep 2006
First published
27 Sep 2006

Chem. Commun., 2006, 4685-4687
Article type
Communication

Tetramethylpyridiniumporphyrazines—a new class of G-quadruplex inducing and stabilising ligands

D. P. N. Gonçalves, R. Rodriguez, S. Balasubramanian and J. K. M. Sanders, Chem. Commun., 2006, 4685
DOI: 10.1039/B611731G

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