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Issue 22, 2006
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Are branched chain fatty acids the natural substrates for P450BM3?

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Abstract

Branched chain fatty acids are substrates for cytochrome P450BM3 (CYP102) from Bacillus megaterium; oxidation of C15 and C17iso and anteiso fatty acids by P450BM3 leads to the formation of hydroxylated products that possess high levels of regiochemical and stereochemical purity.

Graphical abstract: Are branched chain fatty acids the natural substrates for P450BM3?

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Supplementary files

Article information


Submitted
26 Jan 2006
Accepted
16 Mar 2006
First published
30 Mar 2006

Chem. Commun., 2006, 2353-2355
Article type
Communication

Are branched chain fatty acids the natural substrates for P450BM3?

M. J. Cryle, R. D. Espinoza, S. J. Smith, N. J. Matovic and J. J. De Voss, Chem. Commun., 2006, 2353
DOI: 10.1039/B601202G

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