Jump to main content
Jump to site search

Issue 8, 2006
Previous Article Next Article

Anion-templated assembly of [2]rotaxanes

Author affiliations


Anion templation is used to develop a general method for rotaxane synthesis. The anion-templated synthesis of three new [2]rotaxanes containing positively charged pyridinium axles and neutral isophthalamide macrocyclic components is described. The incorporation of electron withdrawing substituents, such as the nitro group, into the 5-position of an isophthalamide bis-vinyl acyclic precursor results in a significant improvement in [2]rotaxane assembly yields. Rotaxane anion binding strengths are also enhanced whilst the rotaxane's unique interlocked binding domain ensures selectivity for chloride – the templating anion – is maintained.

Graphical abstract: Anion-templated assembly of [2]rotaxanes

Back to tab navigation

Publication details

The article was received on 22 Dec 2005, accepted on 09 Feb 2006 and first published on 10 Mar 2006

Article type: Paper
DOI: 10.1039/B518178J
Org. Biomol. Chem., 2006,4, 1529-1538

  •   Request permissions

    Anion-templated assembly of [2]rotaxanes

    M. R. Sambrook, P. D. Beer, M. D. Lankshear, R. F. Ludlow and J. A. Wisner, Org. Biomol. Chem., 2006, 4, 1529
    DOI: 10.1039/B518178J

Search articles by author