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Issue 29, 2006
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Microarrays of heparinoligosaccharides obtained by nitrous acid depolymerization of isolated heparin

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Abstract

Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate–protein interactions.

Graphical abstract: Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

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Publication details

The article was received on 12 Apr 2006, accepted on 01 Jun 2006 and first published on 14 Jun 2006


Article type: Communication
DOI: 10.1039/B605318A
Chem. Commun., 2006, 3116-3118

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    Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

    J. L. de Paz, D. Spillmann and P. H. Seeberger, Chem. Commun., 2006, 3116
    DOI: 10.1039/B605318A

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