Synthetic strategies to chiral organosulfur donors related to bis(ethylenedithio)tetrathiafulvalene

Abstract

Syntheses of enantiopure organosulfur donors by three different strategies requiring only four–six steps are reported. The key step involves either double substitution of an enantiopure cyclic sulfate ester by a dithiolate, attachment of a chiral diol as a ketal, or completely diastereoselective cycloaddition of 1,3-dithiole-2,4,5-trithione to an enantiopure alkene.