Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 6, 2005
Previous Article Next Article

An update on bioactive plant lignans

Author affiliations


Covering: 2000 to 2004

Lignans are a class of secondary plant metabolites produced by oxidative dimerization of two phenylpropanoid units. Although their molecular backbone consists only of two phenylpropane (C6–C3) units, lignans show an enormous structural diversity. There is a growing interest in lignans and their synthetic derivatives due to applications in cancer chemotherapy and various other pharmacological effects. This review deals with lignans possessing anticancer, antioxidant, antimicrobial, anti-inflammatory and immunosuppressive activities, and comprises the data reported in more than 100 peer-reviewed articles, so as to highlight the recently reported bioactive lignans that could be a first step towards the development of potential new therapeutic agents.

Graphical abstract: An update on bioactive plant lignans

Back to tab navigation

Publication details

The article was received on 03 Oct 2005 and first published on 02 Nov 2005

Article type: Review Article
DOI: 10.1039/B514045P
Nat. Prod. Rep., 2005,22, 696-716

  •   Request permissions

    An update on bioactive plant lignans

    M. Saleem, H. J. Kim, M. S. Ali and Y. S. Lee, Nat. Prod. Rep., 2005, 22, 696
    DOI: 10.1039/B514045P

Search articles by author