Issue 2, 2005

Strict preparation and evaluation of water-soluble hat-stacked carbon nanofibers for biomedical application and their high biocompatibility: influence of nanofiber-surface functional groups on cytotoxicity

Abstract

Water-soluble H-CNFs modified with a carboxyl group possessed the ability to induce TNF-α, whereas CHAPS-treated H-CNFs possessed significantly greater activity and were also found to activate NF-κB reporter activity, to a significantly greater level than H-CNFs; furthermore the functional group modified or coated on the surface of H-CNFs was a significant cytotoxic factor that affected cell activation.

Graphical abstract: Strict preparation and evaluation of water-soluble hat-stacked carbon nanofibers for biomedical application and their high biocompatibility: influence of nanofiber-surface functional groups on cytotoxicity

Supplementary files

Article information

Article type
Communication
Submitted
27 Jan 2005
Accepted
17 Mar 2005
First published
01 Apr 2005

Mol. BioSyst., 2005,1, 142-145

Strict preparation and evaluation of water-soluble hat-stacked carbon nanofibers for biomedical application and their high biocompatibility: influence of nanofiber-surface functional groups on cytotoxicity

Y. Sato, K. Shibata, H. Kataoka, S. Ogino, F. Bunshi, A. Yokoyama, K. Tamura, T. Akasaka, M. Uo, K. Motomiya, B. Jeyadevan, R. Hatakeyama, F. Watari and K. Tohji, Mol. BioSyst., 2005, 1, 142 DOI: 10.1039/B501222H

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